Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.48 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.48 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.48 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10506975 | 0.84 | ALDH1A1 (0.71) | CDK4MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL8371672 | 0.84 | CDK4 (0.58) | CDK4MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL8368915 | 0.82 | CDK4 (0.65) | CDK4MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL8367302 | 0.81 | CDK4 (0.56) | CDK4MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL8368653 | 0.80 | MAPT (0.70) | CDK4MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL8368813 | 0.79 | CDK4 (0.53) | CDK4MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL8371662 | 0.79 | CDK4 (0.50) | CDK4MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL19409875 | 0.78 | MAPT (0.61) | CDK4MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL19331529 | 0.78 | CDK4 (0.51) | CDK4MAPTALDH1A1TDP1MEN1 | |
| SCHEMBL8370522 | 0.78 | CDK4 (0.57) | CDK4MAPTALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999052365-A1 | ANTICANCER AGENTS | ELI LILLY AND COMPANY (US) | 1999-10-21 | — | — | WO | disclosed |