Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.57 |
| ▸ | FNTB | P49356 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371075 | 0.85 | FNTA (0.57) | FNTAFNTBCA2ALDH1A1TSHR | |
| SCHEMBL8368841 | 0.81 | FNTA (0.64) | FNTAFNTBCA2ALDH1A1PYGL | |
| SCHEMBL8624885 | 0.79 | FNTA (0.52) | FNTAFNTBCA2ALDH1A1TDP1 | |
| SCHEMBL9770900 | 0.78 | CTSD (0.55) | SMN1; SMN2ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL8670657 | 0.75 | CA2 (0.54) | FNTAFNTBCA2ALDH1A1PYGL | |
| SCHEMBL21579700 | 0.75 | CA2 (0.54) | FNTAFNTBCA2ALDH1A1PYGL | |
| SCHEMBL9134702 | 0.75 | CA2 (0.53) | FNTAFNTBCA2ALDH1A1PYGL | |
| SCHEMBL30952823 | 0.74 | PYGL (0.56) | FNTAFNTBSMN1; SMN2CA2PYGL | |
| SCHEMBL7908196 | 0.74 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL9828354 | 0.73 | CTSD (0.55) | SMN1; SMN2CA2ALDH1A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764149-B1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE POULENC RORER SA (FR) | 1999-01-20 | — | — | EP | disclosed |
| EP-0764149-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995034535-A1 | NOVEL FARNESYL TRANSFERASE INHIBITORS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1995-12-21 | — | — | WO | disclosed |