Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27540296 | 0.93 | CTSD (0.57) | CTSDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8370221 | 0.78 | FNTA (0.57) | ALDH1A1MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL4181143 | 0.76 | PADI1 (0.62) | CAPN1CTSBLMNARAB9ATDP1 | |
| SCHEMBL4960015 | 0.75 | HTT (0.69) | CTSDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL13761295 | 0.74 | ALDH1A1 (0.67) | CTSDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL5508331 | 0.74 | HTT (0.62) | CTSDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL27456509 | 0.73 | CTSD (0.55) | CTSDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9828354 | 0.73 | CTSD (0.55) | CTSDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL2330739 | 0.73 | FNTA (0.53) | CTSDALDH1A1NPSR1TDP1GAA | |
| SCHEMBL2330735 | 0.73 | FNTA (0.53) | CTSDALDH1A1NPSR1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987135-A | Leukemia, melanoma | ISHIHARA SANGYO KAISHA LTD. (JP) | 1991-01-22 | — | — | US | claimed |