Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29277556 | 0.71 | HTT (0.59) | KDM4EPKMALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9626097 | 0.71 | GLP1R (0.35) | MEN1KMT2A | |
| SCHEMBL2122579 | 0.71 | ALDH1A1 (1.00) | KDM4EPKMALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9313173 | 0.71 | ALDH1A1 (1.00) | KDM4EPKMALDH1A1CYP3A4MAPK1 | |
| SCHEMBL4328031 | 0.71 | ALDH1A1 (1.00) | KDM4EPKMALDH1A1CYP3A4MAPK1 | |
| SCHEMBL22742 | 0.71 | ALDH1A1 (1.00) | KDM4EPKMALDH1A1CYP3A4MAPK1 | |
| SCHEMBL7202895 | 0.69 | ALDH1A1 (0.84) | KDM4EPKMALDH1A1CYP3A4MAPK1 | |
| SCHEMBL21028305 | 0.69 | KDM4E (1.00) | KDM4EPKMALDH1A1CYP3A4MAPK1 | |
| SCHEMBL16713293 | 0.69 | ALDH1A1 (0.94) | KDM4EPKMALDH1A1CYP3A4MAPK1 | |
| SCHEMBL25777285 | 0.68 | LMNA (0.47) | KDM4EPKMALDH1A1HTTAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894791-A1 | PYRIMIDINE COMPOUNDS, PROCESS FOR PRODUCING THE SAME, AND AGRICULTURAL OR HORTICULTURAL BACTERICIDES | UBE INDUSTRIES, LTD. (JP) | 1999-02-03 | — | — | EP | disclosed |