Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628429 | 0.78 | SIGMAR1 (0.41) | LMNAEPHX2SMN1; SMN2ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL1677339 | 0.76 | SIGMAR1 (0.40) | LMNAEPHX2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7946281 | 0.75 | ADH1B (0.42) | MMP8MMP2LMNAEPHX2MMP1 | |
| Cyclohexylamine SCHEMBL8575365 | 0.75 | SIGMAR1 (0.38) | MMP8MMP2LMNAEPHX2MMP1 | |
| SCHEMBL11119 | 0.74 | — | — | |
| SCHEMBL17922834 | 0.73 | ALDH1A1 (0.31) | LMNAEPHX2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL1840063 | 0.73 | SMN1; SMN2 (0.46) | LMNAEPHX2SMN1; SMN2ALDH1A1TSHR | |
| Cyclohexylamine SCHEMBL28097700 | 0.72 | TSHR (0.44) | EPHX2ALDH1A1TSHR | |
| Cyclohexylamine SCHEMBL29166025 | 0.71 | MMP8 (0.38) | MMP8MMP2MMP1ALDH1A1TSHR | |
| Fluoride SCHEMBL25246136 | 0.71 | KDM4E (0.42) | LMNASMN1; SMN2ALDH1A1TSHRADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894811-A1 | Copolymers based on insaturated dicarboxylic acid-derivatives and oxyalkylenglycol-alkenylethers | SKW Trostberg Aktiengesellschaft (DE) | 1999-02-03 | — | — | EP | disclosed |