Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1677339 | 0.98 | SIGMAR1 (0.40) | SIGMAR1CHRM2CHRM1CHRM3CYP1A2 | |
| SCHEMBL716430 | 0.82 | SIGMAR1 (0.48) | SIGMAR1CHRM2CHRM1CHRM3CYP1A2 | |
| SCHEMBL7946281 | 0.82 | ADH1B (0.42) | EPHX1LMNAEPHX2SMN1; SMN2ALDH1A1 | |
| SCHEMBL24809947 | 0.79 | SIGMAR1 (0.50) | SIGMAR1CYP1A2EPHX1ALDH1A1NAAA | |
| SCHEMBL27976251 | 0.78 | CYP1A2 (0.48) | SIGMAR1CYP1A2EPHX1LMNAEPHX2 | |
| SCHEMBL1145740 | 0.78 | CYP1A2 (0.48) | SIGMAR1CYP1A2EPHX1LMNAEPHX2 | |
| Cyclohexylamine SCHEMBL8370576 | 0.78 | MMP8 (0.38) | LMNAEPHX2SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL8944543 | 0.77 | CYP1A2 (0.54) | SIGMAR1CHRM2CHRM1CHRM3CYP1A2 | |
| SCHEMBL4660951 | 0.77 | CYP1A2 (0.54) | SIGMAR1CHRM2CHRM1CHRM3CYP1A2 | |
| SCHEMBL20179337 | 0.76 | LMNA (0.34) | SIGMAR1LMNAEPHX2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2012-02-22 | — | — | EP | disclosed |
| EP-0986384-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2012-02-22 | — | — | EP | disclosed |