SCHEMBL8370675

SCHEMBL8370675

Cc1cccc(C)c1-n1sc2ccccc2c1=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPI P34949 11/20 0.61
PMM2 O15305 10/20 0.61
PHOSPHO1 Q8TCT1 8/20 0.61
G6PD P11413 7/20 0.61
CASP3 P42574 3/20 0.61
APOBEC3G Q9HC16 3/20 0.61
KDM4E B2RXH2 2/20 0.61
ALDH1A1 P00352 2/20 0.61
MAPT P10636 2/20 0.61
PKM P14618 2/20 0.61
HPGD P15428 2/20 0.61
ALOX12 P18054 2/20 0.61
NPSR1 Q6W5P4 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
RAB9A P51151 2/20 0.61
NPC1 O15118 1/20 0.61
TP53 P04637 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
KDM5B Q9UGL1 1/20 0.61
HSP90AA1 P07900 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8373425 0.87 PMM2 (0.64) MPIPMM2PHOSPHO1G6PDCASP3
SCHEMBL8372604 0.83 MPI (0.72) MPIPMM2PHOSPHO1G6PDCASP3
SCHEMBL12230490 0.80 MPI (0.65) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL12230488 0.80 MPI (0.73) MPIPMM2PHOSPHO1G6PDAPOBEC3G
SCHEMBL8370659 0.79 G6PD (0.71) MPIPMM2PHOSPHO1G6PDCASP3
SCHEMBL8371739 0.79 MPI (0.62) MPIPMM2PHOSPHO1G6PDCASP3
SCHEMBL8372556 0.78 MPI (0.59) MPIPMM2PHOSPHO1G6PDCASP3
SCHEMBL8373412 0.77 G6PD (0.63) MPIPMM2PHOSPHO1G6PDCASP3
SCHEMBL8370684 0.77 MPI (0.63) MPIPMM2PHOSPHO1G6PDCASP3
SCHEMBL2443755 0.76 MPI (1.00) MPIPMM2PHOSPHO1G6PDCASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210053044-A1 Redox Dehydration Coupling Catalysts and Methods Related Thereto UNIV EMORY (US) 2021-02-25 US disclosed
EP-0644243-B1 Anti-fouling compositions or fouling control of harmful aquatic oranisms SUMITOMO CHEMICAL CO (JP) 1999-01-27 EP disclosed
US-4396413-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1983-08-02 US disclosed
US-4241214-A BACTERICIDE, FUNGICIDE AND ALGAECIDE ROHM AND HAAS COMPANY (US) 1980-12-23 US disclosed
US-4150026-A BACTERICIDES, FUNGICIDES, ALGICIDES ROHM AND HAAS COMPANY (US) 1979-04-17 US disclosed
US-4062946-A 3-ISOTHIAZOLONES ROHM AND HAAS COMPANY (US) 1977-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210053044-A1 Redox Dehydration Coupling Catalysts and Methods Related Thereto SCLY, TST, SQOR MPI 3387/4885PMM2 3056/4885PHOSPHO1 757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.