Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960398 | 0.85 | PLA2G2C (0.36) | TAS1R3TAS1R1CA1CA2HDAC7 | |
| SCHEMBL9189811 | 0.84 | CTSK (0.47) | CTSKCA1CA2 | |
| SCHEMBL963464 | 0.83 | CAD (0.34) | TAS1R3TAS1R1CA1CA2HDAC7 | |
| SCHEMBL3475018 | 0.79 | TGFBR1 (0.39) | TGFBR1 | |
| SCHEMBL8501172 | 0.78 | — | — | |
| SCHEMBL3151163 | 0.74 | — | — | |
| SCHEMBL16585797 | 0.73 | SMN1; SMN2 (0.37) | CTSKPOLB | |
| SCHEMBL28279224 | 0.73 | CTSK (0.41) | EPHX1TAS1R3TAS1R1CTSKCA1 | |
| SCHEMBL302745 | 0.73 | — | — | |
| SCHEMBL8622579 | 0.72 | CA1 (0.31) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221324-B1 | PRODUCTION OF ISOCYANATE FUNCTIONAL ORGANOSILANES | WACKER CHEMIE AG (DE) | 2019-05-01 | — | — | EP | disclosed |
| US-9914744-B2 | Method for producing carbamatoorganosilanes | WACKER CHEMIE AG (DE) | 2018-03-13 | — | — | US | disclosed |
| EP-3221324-A1 | PRODUCTION OF ISOCYANATE FUNCTIONAL ORGANOSILANES | Wacker Chemie AG (DE) | 2017-09-27 | — | — | EP | disclosed |
| EP-3046925-B1 | METHOD FOR PRODUCING CARBAMATOORGANOSILANES | WACKER CHEMIE AG (DE) | 2017-05-31 | — | — | EP | disclosed |
| EP-3046925-A1 | METHOD FOR PRODUCING CARBAMATOORGANOSILANES | Wacker Chemie AG (DE) | 2016-07-27 | — | — | EP | disclosed |
| US-20160200745-A1 | METHOD FOR PRODUCING CARBAMATOORGANOSILANES | WACKER CHEMIE AG (DE) | 2016-07-14 | — | — | US | disclosed |
| WO-2016078891-A1 | PRODUCTION OF ISOCYANATE FUNCTIONAL ORGANOSILANES | WACKER CHEMIE AG (DE) | 2016-05-26 | — | — | WO | disclosed |
| WO-2015040070-A1 | METHOD FOR PRODUCING CARBAMATOORGANOSILANES | WACKER CHEMIE AG (DE) | 2015-03-26 | — | — | WO | disclosed |
| EP-0649850-B1 | Process for making isocyanatoorganosilanes | OSI SPECIALTIES INC (US) | 1999-01-27 | — | — | EP | disclosed |
| EP-0649850-A1 | Process for making isocyanatoorganosilanes | OSi Specialties, Inc. (US) | 1995-04-26 | — | — | EP | disclosed |
| US-5393910-A | Process for making isocyanatoorganosilanes | OSI SPECIALTIES, INC. (US) | 1995-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200745-A1 | METHOD FOR PRODUCING CARBAMATOORGANOSILANES | RCC2, DDT, NPEPPS | EPHX1 2428/4885TAS1R3 4602/4885TAS1R1 4758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.