SCHEMBL3475018

SCHEMBL3475018

C=C(C)C(=O)NC(CCC)[SiH](OC)OC

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.39
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL960398 0.82 PLA2G2C (0.36)
SCHEMBL8370783 0.79 EPHX1 (0.33) TGFBR1
SCHEMBL963464 0.77 CAD (0.34)
SCHEMBL20860864 0.74 ALDH1A1 (0.45) TGFBR1ALDH1A1
SCHEMBL1826412 0.72 TGFBR1 (0.47) TGFBR1ALDH1A1
SCHEMBL10909470 0.72 TGFBR1 (0.47) TGFBR1ALDH1A1
SCHEMBL9189811 0.72 CTSK (0.47)
SCHEMBL10578470 0.71 TGFBR1 (0.40) TGFBR1ALDH1A1
SCHEMBL16593916 0.71 TGFBR1 (0.46) TGFBR1ALDH1A1
SCHEMBL472264 0.71 TGFBR1 (0.46) TGFBR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080114134-A1 Process for crosslinking thermoplastic polymers with silanes employing peroxide blends, the resulting crosslinked thermoplastic polymer composition and articles made therefrom GENERAL ELECTRIC COMPANY (US) 2008-05-15 US claimed
US-20100204409-A1 Process For Crosslinking Thermoplastic Polymers With Silanes Employing Peroxide Blends, The Resulting Crosslinked Thermoplastic Polymer Composition And Articles Made Therefrom MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-12 US disclosed
US-20080114134-A1 Process for crosslinking thermoplastic polymers with silanes employing peroxide blends, the resulting crosslinked thermoplastic polymer composition and articles made therefrom GENERAL ELECTRIC COMPANY (US) 2008-05-15 US disclosed