SCHEMBL837142

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL837775	0.76	ACHE (0.38)	MAPTMEN1KMT2AAPPALDH1A1
	SCHEMBL11044966	0.69	EPHX2 (0.54)	MAPTKMT2AALDH1A1HSD17B10LMNA
	SCHEMBL9617219	0.67	HSPB1 (0.56)	MAPTMEN1KMT2AALDH1A1HSD17B10
	SCHEMBL3274096	0.66	HRH3 (0.55)	MAPTALDH1A1KCNJ1KCNH2LMNA
	SCHEMBL8973048	0.66	MAPT (0.50)	MAPTMEN1KMT2AALDH1A1LMNA
	SCHEMBL3910348	0.65	CYP19A1 (0.50)	MAPTMEN1KMT2AALDH1A1LMNA
	SCHEMBL25583638	0.65	CYP19A1 (0.50)	MAPTMEN1KMT2AALDH1A1LMNA
	SCHEMBL31558431	0.65	ALDH1A1 (0.53)	MAPTMEN1KMT2AAPPALDH1A1
	SCHEMBL22042128	0.65	HSPB1 (0.44)	KMT2AALDH1A1HSD17B10LMNATP53
	SCHEMBL25583651	0.65	CYP19A1 (0.50)	MAPTMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.