Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318592 | 0.83 | WDR5 (0.42) | PGRWDR5OGG1POLBKDM4E | |
| SCHEMBL28227071 | 0.79 | WDR5 (0.40) | PGRWDR5OGG1POLBKDM4E | |
| SCHEMBL9876661 | 0.79 | CYP3A4 (0.52) | POLBTSHRLMNA | |
| SCHEMBL17859584 | 0.78 | HSD11B1 (0.46) | OGG1POLBKDM4ETSHRKMT2A | |
| SCHEMBL9588829 | 0.78 | HSD11B1 (0.49) | OGG1POLBKDM4ETSHRKMT2A | |
| SCHEMBL3374117 | 0.78 | PPARA (0.64) | OGG1KDM4EKMT2ACNR1CNR2 | |
| SCHEMBL11664095 | 0.78 | PGR (0.37) | PGRWDR5OGG1POLBKDM4E | |
| SCHEMBL11662296 | 0.78 | WDR5 (0.40) | PGRWDR5OGG1POLBKDM4E | |
| SCHEMBL11806661 | 0.75 | POLB (0.46) | OGG1POLBKDM4EKMT2ACNR1 | |
| SCHEMBL29893341 | 0.75 | P2RX1 (0.50) | WDR5KCNH2CNR1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5964996-A | ELECTROPHORESIS OF FLUID CONTAINING THE ENANTIOMERS WITH A MACROCYCLIC ANTIBIOTIC, WHICH CAUSES SEQUENTIAL SEPARATION OF ENANTIOMERS BY COMPLEXATION, INCLUSION, HYDROGEN BONDING, DIPOLE STACKING OR STERIC INTERACTION | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1999-10-12 | — | — | US | disclosed |
| US-5874005-A | SEPARATION OF ENANTIOMORPHS IN SOLUTION; CHROMATOGRAPHY, ELECTROPHORESIS | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1999-02-23 | — | — | US | disclosed |
| US-5626757-A | RESOLUTION OF ENANTIOMORPHS BY ELECTROPHORESIS AND CHROMATOGRAPHY | ADVANCED SEPARATION TECHNOLOGIES INC. (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0748247-A1 | MACROCYCLIC ANTIBIOTICS AS SEPARATION AGENTS | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995022390-A1 | MACROCYCLIC ANTIBIOTICS AS SEPARATION AGENTS | CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 1995-08-24 | — | — | WO | disclosed |