SCHEMBL8374342

SCHEMBL8374342

C[Ti](C)(=[SiH2])(Cc1ccccc1)(Cc1ccccc1)(c1cccc2c1Cc1ccccc1-2)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.33
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8373283 0.84 PNMT (0.34) PNMTNPC1RAB9A
SCHEMBL8373279 0.81 PNMT (0.42) PNMTNPC1RAB9A
SCHEMBL8373523 0.73 PNMT (0.35) PNMTNPC1RAB9A
SCHEMBL8373509 0.72 SIGMAR1 (0.39)
SCHEMBL8375971 0.72 SIGMAR1 (0.32)
SCHEMBL8373496 0.69 RAB9A (0.47) PNMTNPC1RAB9A
SCHEMBL7638914 0.67 PNMT (0.50) PNMTNPC1RAB9A
SCHEMBL5823610 0.67 PNMT (0.41) PNMTNPC1RAB9A
SCHEMBL7932874 0.66 PNMT (0.33) PNMTNPC1RAB9A
Hydrochloric Acid SCHEMBL6558664 0.65 PNMT (0.48) PNMTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0659774-B1 Process for producing styrenic polymer IDEMITSU KOSAN CO (JP) 1999-03-03 EP disclosed
US-5623034-A Process for producing styrenic polymer IDEMITSU KOSAN CO., LTD. (JP) 1997-04-22 US disclosed
EP-0497207-B1 Process for purification of styrenic polymer IDEMITSU KOSAN CO (JP) 1996-11-20 EP disclosed
EP-0659774-A2 Process for producing styrenic polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1995-06-28 EP disclosed