Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | MMP16 | P51512 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375406 | 0.84 | MTNR1A (0.43) | CA5AFABP4GAAPKML3MBTL1 | |
| SCHEMBL28195582 | 0.71 | GAA (0.53) | CA5AGAAHSD17B10PKML3MBTL1 | |
| SCHEMBL7387678 | 0.68 | ALDH1A1 (0.49) | GAAL3MBTL1MAPTTSHRALDH1A1 | |
| SCHEMBL16397224 | 0.66 | HSD17B10 (0.50) | HSD17B10L3MBTL1TDP1MMP2MMP12 | |
| SCHEMBL8683168 | 0.66 | CA12 (0.55) | GAAHSD17B10MAPTTSHRALDH1A1 | |
| SCHEMBL21598826 | 0.65 | GAA (0.65) | CA5AFABP4GAAHSD17B10PKM | |
| SCHEMBL8095827 | 0.65 | GAA (0.65) | CA5AFABP4GAAHSD17B10PKM | |
| SCHEMBL752494 | 0.64 | GAA (0.41) | CA5AGAAHSD17B10MAPTTSHR | |
| SCHEMBL3625212 | 0.64 | HSD17B10 (0.51) | CA5AGAAHSD17B10TSHRALDH1A1 | |
| SCHEMBL17006218 | 0.63 | ANO1 (0.47) | CA5AGAAHSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861510-A | Arylsulfonyl hydroxamic acid derivatives as MMP and TNF inhibitors | PFIZER INC (US) | 1999-01-19 | — | — | US | disclosed |