Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375402 | 0.84 | CA5A (0.42) | PKMCA5AALDH1A1FABP4L3MBTL1 | |
| SCHEMBL8377872 | 0.73 | KMT2A (0.43) | MTNR1AMTNR1BALDH1A1L3MBTL1CA1 | |
| SCHEMBL16410344 | 0.71 | MTNR1A (0.51) | MTNR1AMTNR1BKDM4EALDH1A1LMNA | |
| SCHEMBL10728332 | 0.66 | MTNR1A (0.74) | MTNR1AMTNR1BALDH1A1LMNAHTT | |
| SCHEMBL221652 | 0.66 | MTNR1A (0.58) | MTNR1AMTNR1BSTING1ALDH1A1LMNA | |
| SCHEMBL5143612 | 0.65 | MTNR1A (0.47) | MTNR1AMTNR1BSTING1KDM4EALDH1A1 | |
| SCHEMBL28107338 | 0.65 | MTNR1A (0.35) | MTNR1AMTNR1BLMNAL3MBTL1GAA | |
| SCHEMBL27365553 | 0.64 | MTNR1A (0.59) | MTNR1AMTNR1BKDM4ELMNAL3MBTL1 | |
| SCHEMBL7387678 | 0.64 | ALDH1A1 (0.49) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL17772621 | 0.64 | MTNR1A (0.33) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861510-A | Arylsulfonyl hydroxamic acid derivatives as MMP and TNF inhibitors | PFIZER INC (US) | 1999-01-19 | — | — | US | disclosed |