Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 13/20 | 0.59 |
| ▸ | NPC1 | O15118 | 12/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380033 | 0.81 | ALDH1A1 (0.67) | HPGDMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL8376624 | 0.81 | CDH1 (0.54) | HPGDMAPTALDH1A1RECQLRAB9A | |
| SCHEMBL18031151 | 0.80 | NPC1 (0.75) | HPGDMAPTALDH1A1RECQLRAB9A | |
| SCHEMBL10647488 | 0.80 | CYP1A2 (0.64) | HPGDMAPTALDH1A1RECQLRAB9A | |
| SCHEMBL1181029 | 0.80 | NPC1 (0.87) | HPGDMAPTALDH1A1RECQLRAB9A | |
| SCHEMBL2959768 | 0.79 | NPC1 (0.56) | HPGDMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL8375802 | 0.79 | ALDH1A1 (0.61) | HPGDMAPTALDH1A1RAB9ANPC1 | |
| SCHEMBL4104544 | 0.79 | RAB9A (0.59) | HPGDMAPTALDH1A1RECQLRAB9A | |
| SCHEMBL892240 | 0.78 | HPGD (1.00) | HPGDMAPTALDH1A1RECQLRAB9A | |
| SCHEMBL8196656 | 0.78 | NOTUM (0.64) | HPGDMAPTALDH1A1RECQLRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005116-A | HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA | SANKYO COMPANY, LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0885891-A1 | ISOXAZOLE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5221750-A | Chemical intermediate for positive working compound in silver halide emulsion photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| US-4950764-A | HERBICIDES, BACTERICIDES, ANALGESICS, ANTIINFLAMMATORY AGENT | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-21 | — | — | US | disclosed |