Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374641 | 0.89 | GAA (0.46) | SSTR4LMNAPOLBNPC1TP53 | |
| Hydrochloric Acid SCHEMBL8374272 | 0.89 | LMNA (0.42) | SSTR4LMNASMN1; SMN2GAAMAPT | |
| SCHEMBL8374350 | 0.89 | SMN1; SMN2 (0.39) | SSTR4LMNAPOLBNPC1TP53 | |
| Hydrochloric Acid SCHEMBL8809536 | 0.88 | GAA (0.45) | SSTR4LMNAPOLBNPC1TP53 | |
| SCHEMBL8374349 | 0.87 | FAAH (0.40) | SSTR4LMNANPC1TP53RAB9A | |
| SCHEMBL8378285 | 0.86 | LMNA (0.38) | SSTR4LMNAPOLBNPC1TP53 | |
| SCHEMBL8375877 | 0.85 | FAAH (0.46) | LMNAPOLBSMN1; SMN2GAAMAPT | |
| SCHEMBL8374644 | 0.84 | TSHR (0.37) | SSTR4LMNARAB9APKMSMN1; SMN2 | |
| SCHEMBL8374372 | 0.84 | FAAH (0.43) | LMNANPC1MAPTHSD17B10MEN1 | |
| SCHEMBL8374645 | 0.84 | FAAH (0.42) | LMNANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900202-A1 | 3-ALKOXYPYRIDINE-2-CARBOXYLIC ACID AMIDE ESTERS, THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041103-A1 | 3-ALKOXYPYRIDINE-2-CARBOXYLIC ACID AMIDE ESTERS, THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-06 | — | — | WO | disclosed |