Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374644 | 0.91 | TSHR (0.37) | LMNASSTR4SMN1; SMN2HPGDFAAH | |
| SCHEMBL8374350 | 0.88 | SMN1; SMN2 (0.39) | LMNASSTR4ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8375973 | 0.86 | SSTR4 (0.42) | LMNASSTR4ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8811526 | 0.86 | PPIA (0.42) | L3MBTL1 | |
| SCHEMBL7611607 | 0.86 | EGLN2 (0.39) | LMNAALDH1A1SMN1; SMN2HPGDFAAH | |
| SCHEMBL8374641 | 0.84 | GAA (0.46) | LMNASSTR4ALDH1A1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL8374272 | 0.83 | LMNA (0.42) | LMNASSTR4ALDH1A1SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL8809536 | 0.83 | GAA (0.45) | LMNASSTR4ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8374349 | 0.82 | FAAH (0.40) | LMNASSTR4ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL14735535 | 0.82 | MAPT (0.41) | LMNAALDH1A1HPGDFAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900202-A1 | 3-ALKOXYPYRIDINE-2-CARBOXYLIC ACID AMIDE ESTERS, THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997041103-A1 | 3-ALKOXYPYRIDINE-2-CARBOXYLIC ACID AMIDE ESTERS, THEIR PREPARATION AND THEIR USE AS DRUGS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-06 | — | — | WO | disclosed |
| EP-0650960-B1 | Substituted heterocyclic carboxylic acid amide esters, their preparation and their us as medicaments | HOECHST AG (DE) | 1997-03-05 | — | — | EP | disclosed |
| EP-0650960-A1 | Substituted heterocyclic carboxylic acid amide esters, their preparation and their us as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-03 | — | — | EP | disclosed |