Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377411 | 0.89 | TSHR (0.31) | PPARD | |
| SCHEMBL8376446 | 0.87 | MAPT (0.31) | — | |
| SCHEMBL8377387 | 0.83 | KCNH2 (0.30) | — | |
| SCHEMBL8375679 | 0.79 | NPC1 (0.31) | — | |
| SCHEMBL8375800 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL8376904 | 0.78 | ALOX15 (0.36) | PPARD | |
| SCHEMBL5617576 | 0.78 | DPP4 (0.36) | PPARDPPARA | |
| Hydrochloric Acid SCHEMBL8375807 | 0.77 | DPP4 (0.36) | PPARDPPARA | |
| SCHEMBL8378808 | 0.77 | CHRNB2 (0.33) | — | |
| SCHEMBL8377390 | 0.76 | IDO1 (0.46) | PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005116-A | HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA | SANKYO COMPANY, LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0885891-A1 | ISOXAZOLE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |