Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154420 | 0.86 | HTT (0.70) | HTTTRPM8RAB9ATHRBATM | |
| SCHEMBL600597 | 0.86 | HTT (0.70) | HTTTRPM8RAB9ATHRBATM | |
| SCHEMBL12608600 | 0.79 | HTT (0.67) | HTTTRPM8RAB9ATHRBATM | |
| SCHEMBL490213 | 0.79 | THRB (0.50) | TRPM8THRBATMF3SMN1; SMN2 | |
| SCHEMBL4879128 | 0.79 | THRB (0.50) | TRPM8THRBATMF3SMN1; SMN2 | |
| SCHEMBL4906426 | 0.79 | THRB (0.50) | TRPM8THRBATMF3SMN1; SMN2 | |
| SCHEMBL10389595 | 0.78 | HTT (0.56) | HTTTRPM8RAB9ALMNAF3 | |
| SCHEMBL10389594 | 0.78 | HTT (0.56) | HTTTRPM8RAB9ALMNAF3 | |
| SCHEMBL14679431 | 0.75 | HTT (0.62) | HTTRAB9ATHRBATMLMNA | |
| SCHEMBL18364671 | 0.74 | HTT (0.61) | HTTTRPM8RAB9ATHRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901512-A1 | DETERGENT COMPOSITION | UNILEVER PLC (GB) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997044422-A1 | DETERGENT COMPOSITION | UNILEVER PLC (GB) | 1997-11-27 | — | — | WO | disclosed |