Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19323897 | 1.00 | KMT2A (0.48) | KMT2AALDH1A1TRPA1MTNR1AMTNR1B | |
| SCHEMBL19323051 | 0.84 | ALDH1A1 (0.47) | KMT2AALDH1A1TRPA1PGRADRA2A | |
| SCHEMBL7434063 | 0.82 | CES2 (0.43) | KMT2AALDH1A1MTNR1AMTNR1BLMNA | |
| SCHEMBL13127930 | 0.82 | TRPA1 (0.47) | KMT2AALDH1A1TRPA1PGRADRA2A | |
| SCHEMBL24443518 | 0.81 | ALDH1A1 (0.53) | KMT2AALDH1A1TRPA1PGRADRA2A | |
| SCHEMBL14037666 | 0.81 | ALDH1A1 (0.53) | KMT2AALDH1A1TRPA1PGRADRA2A | |
| SCHEMBL10523295 | 0.81 | MTNR1A (0.46) | KMT2AALDH1A1MTNR1AMTNR1BPGR | |
| SCHEMBL8802015 | 0.81 | MTNR1A (0.46) | KMT2AALDH1A1MTNR1AMTNR1BPGR | |
| SCHEMBL19318534 | 0.81 | TRPA1 (0.49) | KMT2AALDH1A1TRPA1PGRADRA2A | |
| SCHEMBL19323031 | 0.81 | PGR (0.47) | KMT2AALDH1A1TRPA1PGRADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253614-A1 | HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS | CHANGZHOU YINSHENG PHARMACEUTICAL CO., LTD. (CN) | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253614-A1 | HEPATITIS C VIRUS INHIBITORS AND USES THEREOF IN PREPARATION OF DRUGS | HAVCR2, HCCS, LIPC | KMT2A 4575/4885ALDH1A1 1148/4885TRPA1 4478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.