Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383726 | 0.90 | CYP11B1 (0.34) | ACACBGRIN2BCYP11B2CYP11B1CYP1A2 | |
| SCHEMBL8380288 | 0.90 | CHRNB1 (0.35) | ACACBCYP11B2GRM2CYP11B1DHODH | |
| SCHEMBL8380281 | 0.87 | KDM1A (0.40) | GRIN2BCYP11B2GRM2KDM1ACYP11B1 | |
| SCHEMBL8517670 | 0.85 | NPY5R (0.34) | ACACBNPY5RGRIN2BPDGFRBPDGFRA | |
| SCHEMBL8380306 | 0.85 | CYP3A4 (0.33) | NPY5RGRIN2BCYP11B2CYP17A1CYP3A4 | |
| SCHEMBL8382675 | 0.84 | HDAC4 (0.35) | HDAC4KDM1A | |
| SCHEMBL8381991 | 0.83 | S1PR3 (0.36) | PDGFRBPDGFRACYP11B2HDAC4CYP11B1 | |
| SCHEMBL9247689 | 0.82 | CHRNB2 (0.34) | NPY5RGRIN2BPDGFRBPDGFRAGRM2 | |
| SCHEMBL8378335 | 0.81 | PDGFRB (0.33) | ACACBGRIN2BPDGFRBPDGFRAPDE5A | |
| SCHEMBL8378334 | 0.81 | PDGFRB (0.33) | ACACBGRIN2BPDGFRBPDGFRAPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475273-B1 | Liquid crystal mixture containing halogenated alcenyl compounds | MERCK PATENT GMBH (DE) | 1999-04-07 | — | — | EP | disclosed |
| EP-0475273-A1 | Halogenated alcenyl compounds | F. HOFFMANN-LA ROCHE AG (CH) | 1992-03-18 | — | — | EP | disclosed |