SCHEMBL838081

SCHEMBL838081

C=C(C)c1ccc(CN(CC(=O)O)CC(=O)O)cc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEP1B Q16820 3/20 0.46
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
HRH3 Q9Y5N1 1/20 0.40
ALDH1A1 P00352 2/20 0.39
PYCR1 P32322 1/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.38
AGTR2 P50052 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ACHE P22303 2/20 0.37
PTPN1 P18031 1/20 0.37
BCHE P06276 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14490540 0.89 MEP1B (0.39) MEP1BHDAC8HDAC6HRH3ALDH1A1
SCHEMBL15083096 0.88 CA1 (0.39) MEP1BHDAC8HDAC6HRH3ACHE
SCHEMBL14199666 0.86 PYCR1 (0.47) ALDH1A1PYCR1POLBMAPTSMN1; SMN2
SCHEMBL2444866 0.81 MEP1B (0.49) MEP1BSMN1; SMN2KMT2A
SCHEMBL16258021 0.80 HRH3 (0.40) MEP1BHDAC8HDAC6HRH3ALDH1A1
SCHEMBL608633 0.79 HRH3 (0.57) HDAC8HDAC6HRH3PYCR1POLB
SCHEMBL14787784 0.79 MEP1B (0.45) MEP1BKMT2A
SCHEMBL13455885 0.77 HDAC8 (0.39) MEP1BHDAC8HDAC6HRH3ALDH1A1
SCHEMBL27220639 0.77 LOXL2 (0.56) MEP1BALDH1A1POLBMAPTSMN1; SMN2
SCHEMBL7557780 0.77 CA2 (0.54) ALDH1A1POLBMAPTHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 EP disclosed
EP-2762326-B1 PRINTING METHOD USING ON PRESS DEVELOPMENT LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORP (JP) 2017-08-23 EP disclosed
EP-3086177-A1 METHOD FOR PREPARING A LITHOGRAPHIC PRINTING PLACE PRECURSOR Fujifilm Corporation (JP) 2016-10-26 EP disclosed
EP-3086176-A1 A LITHOGRAPHIC PRINTING METHOD Fujifilm Corporation (JP) 2016-10-26 EP disclosed
EP-2503393-B2 Method for preparation of lithographic printing plate FUJIFILM CORP (JP) 2016-07-20 EP disclosed
EP-2042312-B1 Processing method of lithographic printing plate precursor FUJIFILM CORP (JP) 2016-05-18 EP disclosed
EP-2088468-B1 Method of preparing lithographic printing plate and lithographic printing plate precursor FUJIFILM CORP (JP) 2016-05-18 EP disclosed
EP-2107422-B1 Method for preparing lithographic printing plate FUJIFILM CORP (JP) 2016-03-30 EP disclosed
EP-2101218-B1 Method for preparing a lithographic printing plate FUJIFILM CORP (JP) 2015-11-25 EP disclosed
US-9032876-B2 Lithographic printing plate precursor, lithographic printing plate platemaking method, and polymerizable monomer FUJIFILM CORPORATION (JP) 2015-05-19 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
EP-1577090-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-06-06 EP disclosed
US-20070072119-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-20070072119-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-20070056457-A1 Lithographic printing plate precursor, lithographic printing method, and novel cyanine dye FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed
US-20070056457-A1 Lithographic printing plate precursor, lithographic printing method, and novel cyanine dye FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed
EP-1759836-A2 Lithographic printing plate precursor, lithographic printing method and cyanine dye Fuji Photo Film Co., Ltd. (JP) 2007-03-07 EP disclosed
US-20070042293-A1 Including an aromatic diphosphonium compound along with an addition polymerization promoter, unsaturated compound, protective layeron an sluminium support; laser recording having excellent ink receptibility during printing and printing durability; strength; on-press development; image strength FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed
US-20070042293-A1 Including an aromatic diphosphonium compound along with an addition polymerization promoter, unsaturated compound, protective layeron an sluminium support; laser recording having excellent ink receptibility during printing and printing durability; strength; on-press development; image strength FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed