Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441755 | 0.83 | MEN1 (0.39) | MEN1KMT2AATMMAPTPOLB | |
| SCHEMBL8380821 | 0.81 | PTAFR (0.33) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL8440546 | 0.79 | NPSR1 (0.38) | MEN1KMT2AMAPTPTGS2NPSR1 | |
| SCHEMBL8443544 | 0.78 | HTR1D (0.36) | MEN1KMT2ATSHRSMN1; SMN2MAPT | |
| SCHEMBL8439249 | 0.78 | KDM4E (0.38) | MEN1KMT2ATSHRSMN1; SMN2MAPT | |
| SCHEMBL8443199 | 0.77 | TDP1 (0.43) | TSHRSMN1; SMN2MAPTPOLBCYP2D6 | |
| SCHEMBL8441858 | 0.76 | CYP2D6 (0.44) | MAPTPOLBCYP2D6DRD2DRD3 | |
| SCHEMBL8672721 | 0.76 | PTGS2 (0.40) | MEN1KMT2ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL8551375 | 0.75 | KDM4E (0.39) | MEN1KMT2ATSHRSMN1; SMN2MAPT | |
| SCHEMBL8668966 | 0.74 | SMN1; SMN2 (0.38) | KMT2ASMN1; SMN2MAPTALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945425-A | ADENOSINE TRIPHOSPHASE INHIBITOR; DNA VIRICIDE | G.D. SEARLE & CO. (US) | 1999-08-31 | — | — | US | claimed |
| US-5945425-A | ADENOSINE TRIPHOSPHASE INHIBITOR; DNA VIRICIDE | G.D. SEARLE & CO. (US) | 1999-08-31 | — | — | US | disclosed |