Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375784 | 0.82 | DHFR (0.63) | DHFR | |
| SCHEMBL11286352 | 0.82 | DHFR (0.68) | DHFR | |
| SCHEMBL8380685 | 0.79 | DHFR (0.63) | DHFR | |
| SCHEMBL28876908 | 0.79 | DHFR (0.63) | DHFR | |
| SCHEMBL3937299 | 0.79 | DHFR (0.68) | DHFR | |
| SCHEMBL380792 | 0.78 | DHFR (0.67) | DHFR | |
| SCHEMBL4468544 | 0.78 | DHFR (0.62) | DHFR | |
| SCHEMBL8376680 | 0.78 | DHFR (0.76) | LMNADHFR | |
| SCHEMBL11601563 | 0.78 | DHFR (0.62) | LMNADHFR | |
| SCHEMBL10846970 | 0.77 | DHFR (0.79) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901473-A1 | NOVEL PIPERAZINYLALKYLTHIOPYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND A PROCESS FOR THE PREPARATION OF THE NOVEL COMPOUNDS | EGIS GYOGYSZERGYAR RT. (HU) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997016429-A1 | NOVEL PIPERAZINYLALKYLTHIOPYRIMIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND A PROCESS FOR THE PREPARATION OF THE NOVEL COMPOUNDS | EGIS Gyógyszergyár Rt. (HU) | 1997-05-09 | — | — | WO | disclosed |