Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 6/20 | 0.48 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 3/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918201 | 0.89 | MAPK1 (0.46) | DHPSALOX5APFEN1ARPDE5A | |
| SCHEMBL8651030 | 0.87 | DHPS (0.48) | DHPSALOX5APFEN1ARPDE5A | |
| SCHEMBL968043 | 0.85 | DHPS (0.46) | DHPSALOX5APFEN1CYP1B1PDE5A | |
| SCHEMBL4581724 | 0.83 | MAPK1 (0.51) | DHPSALOX5APFEN1PDE5ATP53 | |
| SCHEMBL8652149 | 0.80 | MEN1 (0.48) | DHPSCYP1B1TP53MAPK1 | |
| SCHEMBL968044 | 0.78 | NPC1 (0.42) | DHPSCYP1B1TP53RAB9ANPC1 | |
| SCHEMBL8922091 | 0.76 | ALOX5AP (0.42) | DHPSALOX5APFEN1ARPDE5A | |
| SCHEMBL580702 | 0.73 | MEN1 (0.47) | DHPSCYP1B1TP53NPC1SMN1; SMN2 | |
| SCHEMBL29356875 | 0.73 | MEN1 (0.47) | DHPSCYP1B1TP53NPC1SMN1; SMN2 | |
| SCHEMBL8918234 | 0.73 | ALDH1A1 (0.56) | DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942626-A | REACTING A 5-HALO-SUBSTITUTED BENZOTRIAZOLE WITH A MERCAPTO COMPOUND IN THE PRESENCE OF A GROUP 1A METAL OR GROUP 2A COMPOUND FORMING 5-THIO-SUBSTITUTED 2H-BENZOTRIAZOLES HAVING ENHANCED ABSORBANCE AT LONGER WAVELENGTHS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-08-24 | — | — | US | disclosed |
| US-5849821-A | Tris-aryl-s-triazines substituted with biphenylyl groups | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-12-15 | — | — | US | disclosed |
| US-5844026-A | N,N',N''-tris{2,4-bis Hydrocarbyloxy-2,2,6,6-tetra-methylpiperidin-4-yl)alkylamino!-s-triazin-6-yl}-3,3'-ethylenediiminodipropylamines, their isomers and bridged derivatives and polymer compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-12-01 | — | — | US | disclosed |
| US-5726309-A | ULTRAVIOLET RADIATION ABSORBERS; THERMAL STABILIZERS FOR POLYMER SUBSTRATES, ESPECIALLY AUTOMOTIVE COATINGS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-03-10 | — | — | US | disclosed |
| US-5684070-A | FILM WITH TRIAZINE RESORCINOL COMPOUND STABILIZERS FOR RADIATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5681955-A | PHOTOSTABILITY OF POLYMERS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1997-10-28 | — | — | US | disclosed |
| US-5679794-A | ACTINIC LIGHT RESISTANCE, PROCESSING HEAT RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1997-10-21 | — | — | US | disclosed |
| US-5675004-A | POLYMER STABILIZERS TO PROTECT AGAINST ACTINIC RADIATION COVERING MORE OF THE NEAR-UV SPECTRUM; DISCOLORATION INHIBITION; SYNERGISTIC EFFECT WITH HINDERED AMINES; ALKYD, ACRYLIC, URETHANE COATINGS | CIBA-GEIGY CORPORATION (US) | 1997-10-07 | — | — | US | disclosed |
| US-5512621-A | STABILIZER FOR POLYOLEFINS | CIBA-GEIGY CORPORATION (US) | 1996-04-30 | — | — | US | disclosed |