Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8382617 | 0.89 | NAMPT (0.49) | HTTL3MBTL1CHRM3NAMPTPOLB | |
| SCHEMBL8386238 | 0.86 | HTT (0.43) | HTTL3MBTL1NAMPTMAPK1ALDH1A1 | |
| SCHEMBL8386146 | 0.84 | POLB (0.51) | HTTL3MBTL1MAPK1ALDH1A1POLB | |
| SCHEMBL7900157 | 0.84 | ITGB3 (0.51) | HTTL3MBTL1CHRM3NAMPTPOLB | |
| SCHEMBL8385665 | 0.79 | POLB (0.58) | HTTCHRM3NAMPTMAPK1ALDH1A1 | |
| SCHEMBL7913448 | 0.78 | GAA (0.45) | NAMPTALDH1A1POLBTDP1KMT2A | |
| SCHEMBL8384540 | 0.77 | NPC1 (0.46) | HTTMAPK1POLBTDP1 | |
| SCHEMBL11506216 | 0.77 | MAPK1 (0.53) | HTTL3MBTL1MAPK1ALDH1A1POLB | |
| SCHEMBL8385319 | 0.74 | NAMPT (0.47) | HTTL3MBTL1NAMPTPOLBRXFP1 | |
| SCHEMBL8384256 | 0.74 | ALDH1A1 (0.51) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908843-A | Piperazine compounds as fibrinogen inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-06-01 | — | — | US | disclosed |