Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385010 | 0.87 | ELANE (0.50) | LMNAKDM4EALDH1A1SMN1; SMN2MTNR1A | |
| SCHEMBL8385016 | 0.86 | ACHE (0.48) | LMNAMAPK1L3MBTL1ACHEKDM4E | |
| SCHEMBL8381125 | 0.84 | KMT2A (0.44) | LMNAMAPK1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8383409 | 0.83 | LMNA (0.56) | LMNAMAPK1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8381123 | 0.82 | CYSLTR2 (0.52) | — | |
| SCHEMBL8385089 | 0.81 | KMT2A (0.50) | LMNACYP3A4KDM4EALDH1A1MTNR1A | |
| SCHEMBL8381127 | 0.79 | PPARG (0.48) | LMNAMAPK1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL8379807 | 0.78 | DRD4 (0.52) | — | |
| SCHEMBL8383450 | 0.78 | PLA2G4B (0.51) | LMNAKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL8385018 | 0.77 | PTGS1 (0.58) | LMNACYP3A4MAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874436-A | EFFECTIVE IN INHIBITING THE ACTION OF A BACTERIAL HISTIDINE PROTEIN KINASE; USEFUL AGAINST ANTIBIOTIC RESISTANT ORGANISMS | DEMERS JAMES P (US) | 1999-02-23 | — | — | US | disclosed |