Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381125 | 0.90 | KMT2A (0.44) | LMNAMAPK1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL8385080 | 0.88 | ELANE (0.54) | LMNAELANEKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8383452 | 0.86 | LMNA (0.46) | ACHELMNAMAPK1L3MBTL1KDM4E | |
| SCHEMBL8385089 | 0.82 | KMT2A (0.50) | LMNAKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL8383409 | 0.81 | LMNA (0.56) | LMNAMAPK1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27762476 | 0.80 | KMT2A (0.59) | ACHELMNAMAPK1L3MBTL1ELANE | |
| SCHEMBL8381123 | 0.80 | CYSLTR2 (0.52) | — | |
| SCHEMBL8383401 | 0.80 | KIF11 (0.41) | LMNAL3MBTL1ELANEKDM4EALDH1A1 | |
| SCHEMBL8381127 | 0.80 | PPARG (0.48) | LMNAMAPK1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL28584198 | 0.79 | ACHE (0.56) | ACHEKMT2AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874436-A | EFFECTIVE IN INHIBITING THE ACTION OF A BACTERIAL HISTIDINE PROTEIN KINASE; USEFUL AGAINST ANTIBIOTIC RESISTANT ORGANISMS | DEMERS JAMES P (US) | 1999-02-23 | — | — | US | disclosed |