Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384673 | 0.73 | RAPGEF4 (0.35) | TDP1ACHEPTPN1KMT2AALDH1A1 | |
| SCHEMBL22930847 | 0.69 | TDP1 (0.45) | TDP1CYP3A4ACHEPTPN1ALOX15 | |
| SCHEMBL27598104 | 0.69 | CYP3A4 (0.50) | TDP1CYP3A4ACHEPTPN1ALOX15 | |
| SCHEMBL8389832 | 0.68 | SRC (0.53) | TDP1CYP3A4ACHEPTPN1ALOX15 | |
| SCHEMBL9768514 | 0.67 | TDP1 (0.59) | TDP1CYP3A4ACHEPTPN1ALOX15 | |
| SCHEMBL8388304 | 0.67 | CYP3A4 (0.43) | TDP1CYP3A4ACHEALOX15CHRM1 | |
| SCHEMBL29131689 | 0.67 | ALDH1A1 (0.42) | TDP1CYP3A4ALOX15SMN1; SMN2KMT2A | |
| SCHEMBL8427232 | 0.66 | PTPN1 (0.44) | TDP1CYP3A4ACHEPTPN1SMN1; SMN2 | |
| SCHEMBL69242 | 0.64 | CYP3A4 (0.50) | TDP1CYP3A4ACHEALOX15CHRM1 | |
| SCHEMBL67576 | 0.64 | CYP3A4 (0.50) | TDP1CYP3A4ACHEALOX15CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487343-B1 | Process for preparing a lithographic plate | FUJI PHOTO FILM CO LTD (JP) | 1999-04-28 | — | — | EP | disclosed |
| EP-0487343-A1 | Process for preparing a lithographic plate | Fuji Photo Film Co., Ltd. (JP) | 1992-05-27 | — | — | EP | disclosed |