Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3854806 | 0.99 | RAB9A (0.52) | RAB9ASMN1; SMN2LMNAHTTNPC1 | |
| SCHEMBL8390047 | 0.80 | ALDH1A1 (0.52) | RAB9ALMNAHTTNPC1MAPT | |
| Bromide SCHEMBL3853720 | 0.79 | ALDH1A1 (0.55) | RAB9ALMNAHTTNPC1MAPT | |
| SCHEMBL3963629 | 0.79 | CDYL2 (0.48) | RAB9ASMN1; SMN2LMNANPC1MAPT | |
| Bromide SCHEMBL3850385 | 0.78 | RAB9A (0.53) | RAB9ASMN1; SMN2LMNAHTTNPC1 | |
| Bromide SCHEMBL3848238 | 0.78 | NPC1 (0.49) | RAB9ASMN1; SMN2LMNANPC1MAPT | |
| SCHEMBL28150329 | 0.75 | APLNR (0.50) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10749731 | 0.74 | LMNA (0.62) | RAB9ASMN1; SMN2LMNAHTTNPC1 | |
| SCHEMBL2978070 | 0.73 | SMN1; SMN2 (0.65) | RAB9ASMN1; SMN2LMNAHTTNPC1 | |
| SCHEMBL30376093 | 0.72 | SMN1; SMN2 (0.63) | RAB9ASMN1; SMN2LMNAHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6007865-A | FOR INHIBITING AND REVERSING NONENZYMATIC CROSS-LINKING (PROTEIN AGING), TREATING KIDNEY DAMAGE AND TREATING COMPLICATIONS OF DIABETES, PREVENTING FOOD SPOILAGE | ALTEON INC. | 1999-12-28 | — | — | US | claimed |