Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692101 | 0.92 | ALOX5 (0.34) | ALOX5DHFRMAOA | |
| SCHEMBL6680819 | 0.87 | PTGS1 (0.39) | — | |
| SCHEMBL5692254 | 0.84 | NPC1 (0.36) | ALOX5MAOA | |
| SCHEMBL9007397 | 0.80 | — | — | |
| SCHEMBL5692376 | 0.77 | PTGS1 (0.42) | ALOX5 | |
| SCHEMBL5693100 | 0.77 | GABRA1 (0.44) | — | |
| SCHEMBL5692145 | 0.77 | DHFR (0.42) | ALOX5DHFRMAOA | |
| SCHEMBL8389486 | 0.77 | — | — | |
| SCHEMBL7526688 | 0.74 | HMGCR (0.36) | ALOX5 | |
| SCHEMBL8376864 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0910384-A1 | METHOD OF INHIBITING VASCULAR CELL ADHESION MOLECULE-1 AND TREATING CHRONIC INFLAMMATORY DISEASES WITH 2,6-DI-ALKYL-4-SILYL-PHENOLS | HOECHST MARION ROUSSEL, INC. (US) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997040837-A1 | METHOD OF INHIBITING VASCULAR CELL ADHESION MOLECULE-1 AND TREATING CHRONIC INFLAMMATORY DISEASES WITH 2,6-DI-ALKYL-4-SILYL-PHENOLS | HOECHST MARION ROUSSEL, INC. (US) | 1997-11-06 | — | — | WO | disclosed |