Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5692376 | 0.91 | PTGS1 (0.42) | PTGS1PTGS2ALDH1A1TRPA1ATM | |
| SCHEMBL8385658 | 0.87 | ALOX5 (0.32) | — | |
| SCHEMBL9007326 | 0.82 | SCN2A (0.31) | — | |
| SCHEMBL5692263 | 0.77 | PTGS1 (0.50) | PTGS1PTGS2ALDH1A1 | |
| SCHEMBL6676515 | 0.76 | SCN2A (0.43) | ALDH1A1ATM | |
| SCHEMBL5692018 | 0.76 | GABRA1 (0.39) | PTGS1ALDH1A1TRPA1 | |
| SCHEMBL5692101 | 0.76 | ALOX5 (0.34) | ALDH1A1TRPA1ATM | |
| SCHEMBL5692254 | 0.74 | NPC1 (0.36) | PTGS2 | |
| SCHEMBL5693100 | 0.74 | GABRA1 (0.44) | TRPA1ATM | |
| SCHEMBL7517733 | 0.74 | TRPA1 (0.34) | ALDH1A1TRPA1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1468692-A2 | Use of 2,6-di-alkyl-4-silyl-phenols for treating xanthoma | MERRELL PHARMACEUTICALS INC. (US) | 2004-10-20 | — | — | EP | disclosed |