Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 4/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | CFD | P00746 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8172515 | 0.88 | LMNA (0.68) | PPARDPPARGPPARAALDH1A1LMNA | |
| SCHEMBL8388314 | 0.84 | ALDH1A1 (0.61) | MPOALDH1A1LMNAL3MBTL1 | |
| SCHEMBL13930965 | 0.82 | PPARD (0.77) | PPARDPPARGPPARAALDH1A1LMNA | |
| SCHEMBL3919503 | 0.82 | THRA (0.48) | MPOPPARDPPARGPPARAALDH1A1 | |
| SCHEMBL8387016 | 0.81 | MPO (0.47) | MPOPPARDPPARGPPARAMAPK14 | |
| SCHEMBL8388829 | 0.80 | ALDH1A1 (0.48) | MPOALDH1A1LMNAFAAH | |
| SCHEMBL5639523 | 0.80 | PPARD (0.60) | PPARDPPARGPPARAALDH1A1LMNA | |
| SCHEMBL8175259 | 0.79 | PPARD (0.66) | PPARDPPARGPPARAALDH1A1LMNA | |
| SCHEMBL8174606 | 0.79 | PPARD (0.72) | PPARDPPARGPPARAALDH1A1LMNA | |
| SCHEMBL8171659 | 0.78 | PPARD (0.82) | PPARDPPARGPPARAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877199-A | ALZHEIMER'S DISEASE; SEDATIVE | SANKYO COMPANY, LIMITED (JP) | 1999-03-02 | — | — | US | disclosed |
| EP-0804416-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY LIMITED (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |