Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4254894 | 0.77 | SIGMAR1 (1.00) | SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL158734 | 0.77 | SIGMAR1 (0.67) | SIGMAR1L3MBTL1NPC1RAB9AGAA | |
| SCHEMBL4498508 | 0.76 | SIGMAR1 (0.66) | SIGMAR1L3MBTL1S1PR1S1PR3S1PR5 | |
| SCHEMBL28897720 | 0.76 | LMNA (0.72) | NPC1RAB9AKDM4E | |
| SCHEMBL13917983 | 0.75 | S1PR1 (0.75) | SIGMAR1L3MBTL1S1PR1S1PR3S1PR5 | |
| SCHEMBL10468745 | 0.75 | HDAC3 (0.71) | SIGMAR1L3MBTL1S1PR1S1PR3S1PR5 | |
| SCHEMBL28079976 | 0.75 | L3MBTL1 (0.56) | SIGMAR1L3MBTL1NPC1RAB9AGAA | |
| SCHEMBL2538905 | 0.75 | SIGMAR1 (0.95) | SIGMAR1DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL4987504 | 0.75 | LMNA (0.56) | SIGMAR1NPC1RAB9AGAAKDM4E | |
| SCHEMBL9543983 | 0.75 | SIGMAR1 (0.58) | SIGMAR1L3MBTL1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977132-A | GALACTORRHEA, HYPERPROLACTINEMIC OVULATION, PROLACTINOMA AND BRAIN TUMORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-11-02 | — | — | US | disclosed |