Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897614 | 0.84 | NPC1 (0.58) | L3MBTL1NPC1HPGDRAB9AGAA | |
| SCHEMBL27715529 | 0.83 | L3MBTL1 (0.50) | L3MBTL1NPC1HPGDRAB9AGAA | |
| SCHEMBL27625428 | 0.82 | EPHX2 (0.50) | L3MBTL1NPC1HPGDRAB9AGAA | |
| Hydrochloric Acid SCHEMBL5695093 | 0.80 | L3MBTL1 (0.51) | L3MBTL1HPGDSIGMAR1KMT2ACYP2D6 | |
| SCHEMBL27964413 | 0.77 | CA12 (0.52) | L3MBTL1NPC1HPGDRAB9AGAA | |
| SCHEMBL6429495 | 0.76 | THRB (0.48) | HPGDGAAEPHX2KMT2AEPHX1 | |
| SCHEMBL5840065 | 0.76 | L3MBTL1 (0.68) | L3MBTL1NPC1HPGDRAB9AGAA | |
| SCHEMBL28871071 | 0.76 | EPHX1 (0.53) | NPC1RAB9AGAAEPHX2KMT2A | |
| SCHEMBL8388448 | 0.75 | SIGMAR1 (0.60) | L3MBTL1NPC1HPGDRAB9AGAA | |
| SCHEMBL15093821 | 0.75 | EPHX2 (0.86) | L3MBTL1NPC1HPGDRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777706-A | 3-[(benzo[d][1,3]dioxolane-4-yl)-oxy]-3-arylpropylamine compound and application thereof | 江苏恩华药业股份有限公司 | 2016-07-20 | — | — | CN | disclosed |