Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17972846 | 0.84 | ALDH1A1 (0.41) | TSHRALDH1A1TDP1POLBLMNA | |
| SCHEMBL2499899 | 0.83 | TSHR (0.50) | TSHRALDH1A1TRPA1ATMHSP90AA1 | |
| SCHEMBL2173229 | 0.77 | ALDH1A1 (0.46) | TSHRALDH1A1TRPA1ATMTDP1 | |
| SCHEMBL8392134 | 0.75 | CYP3A4 (0.48) | TSHRALDH1A1TDP1CA2CA1 | |
| SCHEMBL17972850 | 0.75 | TAAR1 (0.42) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL30728872 | 0.75 | TAAR1 (0.42) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL7848673 | 0.75 | TRPA1 (0.37) | TSHRALDH1A1TRPA1ATMTDP1 | |
| SCHEMBL9259048 | 0.74 | TSHR (0.50) | TSHRALDH1A1TRPA1ATMTDP1 | |
| SCHEMBL8387507 | 0.71 | CA2 (0.46) | TSHRALDH1A1HSP90AA1TDP1CA2 | |
| SCHEMBL419708 | 0.69 | ALDH1A1 (0.52) | TSHRALDH1A1TRPA1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750607-B1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |