SCHEMBL29369964

SCHEMBL29369964

N[C@@H](Cc1cc(CP(=O)(O)O)cc(-c2ccccc2Cl)c1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 1.00
▸ ALOX15 P16050 2/20 1.00
▸ CYP2C19 P33261 2/20 1.00
▸ KMT2A Q03164 2/20 1.00
▸ HSD17B10 Q99714 2/20 1.00
▸ TDP1 Q9NUW8 1/20 1.00
▸ MAPK1 P28482 2/20 0.60
▸ ALDH1A1 P00352 1/20 0.53
▸ CYP1A2 P05177 1/20 0.53
▸ CYP2C9 P11712 1/20 0.53
▸ HPGD P15428 1/20 0.53
▸ TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2394195 1.00 MEN1 (1.00) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL2394204 1.00 MEN1 (1.00) MEN1ALOX15CYP2C19KMT2AHSD17B10
Ammonia Solution, Strong SCHEMBL29580190 0.99 MEN1 (0.98) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL794085 0.85 MEN1 (0.73) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL1430608 0.85 MEN1 (0.73) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL20693802 0.84 MEN1 (0.72) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL838875 0.84 MEN1 (0.72) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL30545232 0.84 MEN1 (0.72) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL838874 0.84 MEN1 (0.72) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL9344811 0.81 MEN1 (0.69) MEN1ALOX15CYP2C19KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4509120-A2 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF Amylyx Pharmaceuticals Inc. (US) 2025-02-19 — — EP claimed
US-12186330-B2 Compositions for improving cell viability and methods of use thereof Amylyx Pharmaceuticals Inc. (US) 2025-01-07 — — US claimed
EP-4475953-A1 NMDAR ANTAGONISTS PREVENT AGEING AND AGING-ASSOCIATED CONDITIONS AND DISEASES THROUGH INCREASING 20S PROTEASOME ACTIVITY SAHIN, Fikret (TR) 2024-12-18 — — EP claimed
CN-119095622-A NMDAR antagonists prevent aging and aging-related conditions and diseases by increasing 20S proteasome activity 菲克雷特·萨欣 2024-12-06 — — CN claimed
WO-2023154014-A1 NMDAR ANTAGONISTS PREVENT AGEING AND AGING-ASSOCIATED CONDITIONS AND DISEASES THROUGH INCREASING 20S PROTEASOME ACTIVITY SAHIN FIKRET (TR) 2023-08-17 — — WO claimed
US-20220160733-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF Amylyx Pharmaceuticals Inc. 2022-05-26 — — US claimed
US-12637450-B2 Tri-substituted aryl and heteroaryl derivatives as modulators of PI3-kinase and autophagy pathways GLOBAL CANCER TECHNOLOGY INC. (US) 2026-05-26 — — US disclosed
US-20250275985-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF AMYLYX PHARMACEUTICALS, INC. 2025-09-04 — — US disclosed
US-12357635-B2 Nanocarriers and their processing for diagnostics and therapeutics RHODE ISLAND HOSPITAL (US) 2025-07-15 — — US disclosed
EP-3774783-B1 TRI-SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF PI3-KINASE AND AUTOPHAGY PATHWAYS NEUROPORE THERAPIES INC (US) 2025-06-04 — — EP disclosed
US-20250161238-A1 NMDAR Antagonists Prevent Ageing and Aging-Associated Conditions and Diseases Through Increasing 20S Proteasome Activity SAHIN FIKRET (TR) 2025-05-22 — — US disclosed
EP-4509120-A2 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF Amylyx Pharmaceuticals Inc. (US) 2025-02-19 — — EP disclosed
US-12186330-B2 Compositions for improving cell viability and methods of use thereof Amylyx Pharmaceuticals Inc. (US) 2025-01-07 — — US disclosed
US-11345713-B2 Compounds as modulators of TLR2 signaling NEUROPORE THERAPIES, INC. (US) 2022-05-31 — — US disclosed
US-20220160733-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF Amylyx Pharmaceuticals Inc. 2022-05-26 — — US disclosed
US-20220110948-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF AMYLYX PHARMACEUTICALS, INC. 2022-04-14 — — US disclosed
US-11299487-B2 Compounds and compositions as modulators of TLR signaling NEUROPORE THERAPIES, INC. (US) 2022-04-12 — — US disclosed
WO-2022067114-A1 COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING NEUROPORE THERAPIES, INC. (US) 2022-03-31 — — WO disclosed
EP-3946599-A1 COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING Neuropore Therapies, Inc. (US) 2022-02-09 — — EP disclosed
US-11236079-B2 Morpholine derivates as inhibitors of Vps34 NEUROPORE THERAPIES, INC. (US) 2022-02-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220160733-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF HSPA9, CYP27A1, TUFM MEN1 4437/4885ALOX15 532/4885CYP2C19 2671/4885
US-20250275985-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF HSPA9, CYP27A1, TUFM MEN1 4437/4885ALOX15 532/4885CYP2C19 2671/4885
US-12357635-B2 Nanocarriers and their processing for diagnostics and therapeutics SYVN1, SSB, TNF MEN1 3527/4885ALOX15 2293/4885CYP2C19 4627/4885
US-12637450-B2 Tri-substituted aryl and heteroaryl derivatives as modulators of PI3-kinase and autophagy pathways PIK3R4, PIK3R1, ATG7 MEN1 4728/4885ALOX15 3896/4885CYP2C19 3997/4885
US-20220110948-A1 COMPOSITIONS FOR IMPROVING CELL VIABILITY AND METHODS OF USE THEREOF HSPA9, CYP27A1, TUFM MEN1 4437/4885ALOX15 532/4885CYP2C19 2671/4885
US-11345713-B2 Compounds as modulators of TLR2 signaling TLR2, TLR4, TLR3 MEN1 4870/4885ALOX15 1657/4885CYP2C19 4881/4885
US-12186330-B2 Compositions for improving cell viability and methods of use thereof HSPA9, CYP27A1, TUFM MEN1 4437/4885ALOX15 532/4885CYP2C19 2671/4885
US-11236079-B2 Morpholine derivates as inhibitors of Vps34 VPS35, TFEB, VPS4B MEN1 3272/4885ALOX15 4813/4885CYP2C19 4843/4885
US-11299487-B2 Compounds and compositions as modulators of TLR signaling TLR3, TLR6, TLR4 MEN1 4878/4885ALOX15 1693/4885CYP2C19 4853/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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