Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13012989 | 0.86 | ALDH1A1 (0.53) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL634085 | 0.80 | ALDH1A1 (0.79) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL17886497 | 0.80 | ALDH1A1 (0.50) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL15199346 | 0.76 | ALDH1A1 (0.57) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL13500312 | 0.74 | PARG (0.56) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL8389751 | 0.74 | ALDH1A1 (0.56) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL12169331 | 0.73 | ALDH1A1 (0.55) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL10282879 | 0.73 | ALDH1A1 (0.56) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL11782254 | 0.73 | MMP2 (0.56) | ALDH1A1GAASMN1; SMN2CA2CA1 | |
| SCHEMBL7765161 | 0.73 | ALDH1A1 (0.55) | ALDH1A1GAASMN1; SMN2CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560473-B2 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES, P.L.A. (CN) | 2009-07-14 | — | — | US | claimed |
| CN-1250519-C | Amine derivative with K channel regulation function and its preparing process and application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2006-04-12 | — | — | CN | claimed |
| CN-1250518-C | Amine derivative for preventing ischemic and anoxia damage of nerve and its medical application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2006-04-12 | — | — | CN | claimed |
| CN-1205175-C | Amine derivative possessing the function of anti-pulmonary hypertension and its application in pharmacological science | INST OF TOXICANT AND MEDICAMEN (CN) | 2005-06-08 | — | — | CN | claimed |
| US-20040266822-A1 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. (CN) | 2004-12-30 | — | — | US | claimed |
| EP-1386908-A1 | AMINE DERIVATIVE WITH POTASSIUM CHANNEL REGULATORY FUNCTION, ITS PREPARATION AND USE | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. (CN) | 2004-02-04 | — | — | EP | claimed |
| CN-1415596-A | Amine derivative possessing the function of anti-pulmonary hypertension and its application in pharmacological science | INST OF TOXICANT AND MEDICAMEN (CN) | 2003-05-07 | — | — | CN | claimed |
| CN-1365967-A | Amine derivative with K channel regulation function and its preparing process and application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2002-08-28 | — | — | CN | claimed |
| CN-1365966-A | Amine derivative for preventing ischemic and anoxia damage of nerve and its medical application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2002-08-28 | — | — | CN | claimed |
| CN-117924125-A | Method for preparing sulfonamide derivative through visible light catalysis without metal participation | 苏州大学 | 2024-04-26 | — | — | CN | disclosed |
| EP-1386908-B1 | AMINE DERIVATIVE WITH POTASSIUM CHANNEL REGULATORY FUNCTION, ITS PREPARATION AND USE | INST PHARM & TOXICOLOGY AMMS (CN) | 2010-03-03 | — | — | EP | disclosed |
| US-7560473-B2 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES, P.L.A. (CN) | 2009-07-14 | — | — | US | disclosed |
| CN-1250519-C | Amine derivative with K channel regulation function and its preparing process and application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2006-04-12 | — | — | CN | disclosed |
| CN-1250518-C | Amine derivative for preventing ischemic and anoxia damage of nerve and its medical application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2006-04-12 | — | — | CN | disclosed |
| CN-1205175-C | Amine derivative possessing the function of anti-pulmonary hypertension and its application in pharmacological science | INST OF TOXICANT AND MEDICAMEN (CN) | 2005-06-08 | — | — | CN | disclosed |
| US-20040266822-A1 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. (CN) | 2004-12-30 | — | — | US | disclosed |
| EP-1386908-A1 | AMINE DERIVATIVE WITH POTASSIUM CHANNEL REGULATORY FUNCTION, ITS PREPARATION AND USE | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. (CN) | 2004-02-04 | — | — | EP | disclosed |
| CN-1415596-A | Amine derivative possessing the function of anti-pulmonary hypertension and its application in pharmacological science | INST OF TOXICANT AND MEDICAMEN (CN) | 2003-05-07 | — | — | CN | disclosed |
| CN-1365966-A | Amine derivative for preventing ischemic and anoxia damage of nerve and its medical application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2002-08-28 | — | — | CN | disclosed |
| CN-1365967-A | Amine derivative with K channel regulation function and its preparing process and application | INST OF TOXIC MEDICAL MATERIAL (CN) | 2002-08-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266822-A1 | Amine derivative with potassium channel regulatory function, its preparation and use | KCNMA1, KCNA5, KCNA1 | ALDH1A1 428/4885GAA 4048/4885SMN1; SMN2 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.