Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8389088 | 0.84 | ALDH1A1 (0.44) | ALDH1A1MAPTTK1CYP2C9CYP2C19 | |
| SCHEMBL8073601 | 0.84 | ALDH1A1 (0.51) | ALDH1A1RAB9AMAPTSTAT1NPSR1 | |
| SCHEMBL7847521 | 0.82 | LMNA (0.41) | ALDH1A1RAB9AMAPTNPSR1POLB | |
| SCHEMBL8389872 | 0.81 | TP53 (0.35) | ALDH1A1RAB9AMAPTSTAT1NPSR1 | |
| SCHEMBL7846211 | 0.79 | MEN1 (0.36) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL10070151 | 0.78 | ALDH1A1 (0.37) | ALDH1A1RAB9AMAPTSTAT1NPSR1 | |
| SCHEMBL9009278 | 0.78 | TP53 (0.37) | ALDH1A1MAPTTP53 | |
| SCHEMBL9009456 | 0.78 | ALDH1A1 (0.46) | ALDH1A1RAB9AMAPTSTAT1NPSR1 | |
| SCHEMBL7849696 | 0.78 | HSD17B10 (0.48) | ALDH1A1MAPTPOLBKMT2AHSD17B10 | |
| SCHEMBL7847748 | 0.77 | MAPT (0.41) | ALDH1A1RAB9AMAPTNPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912526-A1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 1999-05-06 | — | — | EP | claimed |
| WO-1997043266-A1 | ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1997-11-20 | — | — | WO | claimed |