Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399115 | 0.92 | MTNR1A (0.40) | LTB4R2LMNAKMT2ANPC1RAB9A | |
| SCHEMBL8396412 | 0.91 | SMN1; SMN2 (0.40) | LTB4R2PPARASMN1; SMN2HTTHSD17B10 | |
| SCHEMBL8396078 | 0.88 | LTB4R2 (0.40) | LTB4R2HPGDTP53LMNAMEN1 | |
| SCHEMBL8396071 | 0.88 | LTB4R2 (0.36) | LTB4R2TP53LMNARAB9A | |
| SCHEMBL8398137 | 0.88 | RAB9A (0.40) | LTB4R2MAPTTP53LMNAMEN1 | |
| SCHEMBL8399085 | 0.88 | LTB4R2 (0.40) | LTB4R2TP53LMNAMEN1KMT2A | |
| SCHEMBL8399483 | 0.87 | HDAC6 (0.39) | LTB4R2MAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8399605 | 0.86 | LTB4R2 (0.39) | LTB4R2HPGDFFAR1FFAR4MAPT | |
| SCHEMBL8398957 | 0.86 | AKR1A1 (0.43) | — | |
| SCHEMBL8395274 | 0.86 | AKR1B1 (0.37) | HPGDSMN1; SMN2TP53ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |