Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395164 | 0.93 | CYP3A4 (0.41) | CYP3A4LMNARECQLTRPM8SLC1A5 | |
| SCHEMBL8398724 | 0.92 | NISCH (0.38) | CYP3A4LMNARECQLSLC1A5NPSR1 | |
| SCHEMBL9241220 | 0.91 | RECQL (0.41) | CYP3A4LMNARECQLSLC1A5CDK4 | |
| SCHEMBL8395439 | 0.90 | CYP3A4 (0.43) | CYP3A4LMNARECQLRXRARXRB | |
| SCHEMBL8398007 | 0.89 | SMN1; SMN2 (0.39) | CYP3A4LMNARECQLKMT2AMEN1 | |
| SCHEMBL8395678 | 0.89 | MRGPRX4 (0.39) | CYP3A4LMNARECQLKMT2AMEN1 | |
| SCHEMBL8399135 | 0.89 | CYP3A4 (0.43) | CYP3A4LMNAKMT2AMEN1MAPT | |
| SCHEMBL8399129 | 0.88 | LMNA (0.41) | CYP3A4LMNATRPM8SLC1A5NPSR1 | |
| SCHEMBL8396234 | 0.88 | PPARD (0.39) | CYP3A4LMNASLC1A5 | |
| SCHEMBL8399060 | 0.88 | TP53 (0.45) | LMNARXRARXRBTRPM8SLC1A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |