Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395408 | 0.93 | CYP3A4 (0.43) | CYP3A4LMNAMAPTTDP1RECQL | |
| SCHEMBL8398724 | 0.89 | NISCH (0.38) | CYP3A4LMNAL3MBTL1MAPTTDP1 | |
| SCHEMBL8399135 | 0.88 | CYP3A4 (0.43) | CYP3A4LMNAMAPTTDP1MEN1 | |
| SCHEMBL8398841 | 0.87 | L3MBTL1 (0.42) | LMNAL3MBTL1MAPTRAB9AMAPK1 | |
| SCHEMBL9241220 | 0.86 | RECQL (0.41) | CYP3A4LMNAL3MBTL1MAPTRECQL | |
| SCHEMBL8399060 | 0.85 | TP53 (0.45) | LMNAL3MBTL1MAPTRAB9ATDP1 | |
| SCHEMBL8399129 | 0.85 | LMNA (0.41) | CYP3A4LMNAL3MBTL1MAPTMAPK1 | |
| SCHEMBL8396234 | 0.85 | PPARD (0.39) | CYP3A4LMNASLC1A5 | |
| SCHEMBL8395678 | 0.84 | MRGPRX4 (0.39) | CYP3A4LMNAL3MBTL1MAPTRAB9A | |
| SCHEMBL8398007 | 0.84 | SMN1; SMN2 (0.39) | CYP3A4LMNAL3MBTL1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |