Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399054 | 0.92 | MEN1 (0.43) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8398724 | 0.91 | NISCH (0.38) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8398948 | 0.89 | LMNA (0.41) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8395408 | 0.88 | CYP3A4 (0.43) | LMNAMEN1KMT2AMAPTTRPM8 | |
| SCHEMBL8396234 | 0.87 | PPARD (0.39) | LMNATHRBLTB4RLTB4R2SLC1A5 | |
| SCHEMBL8399060 | 0.87 | TP53 (0.45) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8398993 | 0.87 | KMT2A (0.41) | LMNAMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL8395326 | 0.87 | LMNA (0.43) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8397821 | 0.86 | RXRA (0.41) | LMNAMAPK1MRGPRX4MAOB | |
| SCHEMBL8519936 | 0.85 | NISCH (0.36) | LMNAMEN1KMT2AL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |