Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395408 | 0.89 | CYP3A4 (0.43) | CYP3A4LMNAKMT2AMEN1MAPT | |
| SCHEMBL8395164 | 0.88 | CYP3A4 (0.41) | CYP3A4LMNAKMT2AMEN1MAPT | |
| SCHEMBL8398969 | 0.86 | MAPT (0.39) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8398724 | 0.85 | NISCH (0.38) | CYP3A4LMNAKMT2AMEN1MAPT | |
| SCHEMBL8399105 | 0.84 | FFAR1 (0.39) | CYP3A4LMNAKMT2AMEN1MAPT | |
| SCHEMBL8395954 | 0.84 | HIF1A (0.41) | CYP3A4LMNAKMT2AMEN1MAPT | |
| SCHEMBL8400198 | 0.84 | TDP1 (0.40) | CYP3A4LMNAKMT2AMEN1MAPT | |
| SCHEMBL8400207 | 0.83 | CYP3A4 (0.38) | CYP3A4LMNAKMT2AMEN1MAPT | |
| SCHEMBL8398948 | 0.83 | LMNA (0.41) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL8398007 | 0.83 | SMN1; SMN2 (0.39) | CYP3A4LMNAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |