SCHEMBL8395678

SCHEMBL8395678

CCN(C(=O)C=NOC)c1ccccc1COc1ccc(C)cc1C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP3A4 P08684 2/20 0.38
LMNA P02545 2/20 0.38
RECQL P46063 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
KDM4E B2RXH2 1/20 0.37
FFAR4 Q5NUL3 5/20 0.36
FFAR1 O14842 2/20 0.36
HIF1A Q16665 1/20 0.36
HPGD P15428 2/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
CASP3 P42574 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SENP8 Q96LD8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8398007 0.92 SMN1; SMN2 (0.39) MEN1KMT2ACYP3A4LMNARECQL
SCHEMBL8400208 0.90 MEN1 (0.46) MRGPRX4MEN1KMT2AFFAR4FFAR1
SCHEMBL8395408 0.89 CYP3A4 (0.43) MEN1KMT2ACYP3A4LMNARECQL
SCHEMBL8397935 0.88 MRGPRX4 (0.41) MRGPRX4LMNARECQLL3MBTL1FFAR4
SCHEMBL9241220 0.87 RECQL (0.41) KMT2ACYP3A4LMNARECQLL3MBTL1
SCHEMBL8398724 0.86 NISCH (0.38) MEN1KMT2ACYP3A4LMNARECQL
SCHEMBL8399105 0.85 FFAR1 (0.39) MEN1KMT2ACYP3A4LMNAL3MBTL1
SCHEMBL8395954 0.84 HIF1A (0.41) MEN1KMT2ACYP3A4LMNAL3MBTL1
SCHEMBL8395164 0.84 CYP3A4 (0.41) MEN1KMT2ACYP3A4LMNARECQL
SCHEMBL8400207 0.84 CYP3A4 (0.38) MEN1KMT2ACYP3A4LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644183-B1 Process of producing N-alkylacetamides SHIONOGI & CO (JP) 1999-06-02 EP disclosed
US-5498792-A Process of producing N-alkylacetamides SHIONOGI & CO., LTD. (JP) 1996-03-12 US disclosed
EP-0644183-A2 Process of producing N-alkylacetamides SHIONOGI & CO., LTD. (JP) 1995-03-22 EP disclosed