Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395524 | 0.85 | AKR1B1 (0.43) | L3MBTL1AKR1B1MAPTKMT2AHTT | |
| SCHEMBL8396268 | 0.84 | AKR1B1 (0.41) | AKR1B1MAPTMEN1KMT2AHTT | |
| SCHEMBL8396103 | 0.83 | AKR1B1 (0.41) | AKR1B1MAPTHTTALDH1A1RAB9A | |
| SCHEMBL8399286 | 0.82 | AKR1B1 (0.39) | AKR1B1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8395190 | 0.82 | L3MBTL1 (0.44) | L3MBTL1MAPTMEN1KMT2AHTT | |
| SCHEMBL8395800 | 0.82 | AKR1B1 (0.41) | AKR1B1MEN1KMT2AROCK2GRK2 | |
| SCHEMBL8395318 | 0.81 | AKR1B1 (0.46) | L3MBTL1AKR1B1MAPTMEN1KMT2A | |
| SCHEMBL8399351 | 0.79 | AKR1B1 (0.46) | AKR1B1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8395489 | 0.77 | AKR1B1 (0.39) | L3MBTL1AKR1B1MAPTMEN1KMT2A | |
| SCHEMBL8399294 | 0.76 | AKR1B1 (0.39) | AKR1B1MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |