Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 6/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395524 | 0.88 | AKR1B1 (0.43) | AKR1B1NPC1RAB9AMAPTHTT | |
| SCHEMBL8396103 | 0.86 | AKR1B1 (0.41) | AKR1B1NPC1RAB9AMAPTHTT | |
| SCHEMBL8399286 | 0.85 | AKR1B1 (0.39) | AKR1B1ADRA2CRAB9AMAPTALDH1A1 | |
| SCHEMBL8395800 | 0.85 | AKR1B1 (0.41) | AKR1B1ADRA2CMEN1KMT2AADRA2B | |
| SCHEMBL8399103 | 0.84 | L3MBTL1 (0.43) | AKR1B1NPC1RAB9APKMMAPT | |
| SCHEMBL8399351 | 0.82 | AKR1B1 (0.46) | AKR1B1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8399294 | 0.81 | AKR1B1 (0.39) | AKR1B1MAPTALDH1A1 | |
| SCHEMBL8398164 | 0.81 | ADRA2C (0.40) | AKR1B1ADRA2CNPC1RAB9APKM | |
| SCHEMBL8399258 | 0.80 | AKR1B1 (0.45) | AKR1B1 | |
| SCHEMBL8399262 | 0.80 | AKR1B1 (0.40) | AKR1B1NPC1RAB9AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |