Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395544 | 0.89 | GAA (0.43) | MEN1KMT2AALDH1A1CCNE1CDK2 | |
| SCHEMBL8395427 | 0.88 | EGFR (0.38) | MEN1KMT2ANPC1MAPTERBB2 | |
| SCHEMBL8399066 | 0.87 | CYP1A2 (0.35) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8397890 | 0.84 | RAB9A (0.37) | SMN1; SMN2NPC1RAB9AALDH1A1CCNE1 | |
| SCHEMBL8396283 | 0.83 | SYK (0.45) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8396076 | 0.83 | MEN1 (0.34) | NOS1MEN1KMT2AMAPT | |
| SCHEMBL8399113 | 0.83 | NOS1 (0.44) | NOS1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL8399428 | 0.80 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2HPGDNPC1 | |
| SCHEMBL8395622 | 0.80 | KDM4E (0.41) | NOS1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL8395603 | 0.80 | AKR1B1 (0.47) | NOS1MEN1KMT2ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |