Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.47 |
| ▸ | GABRE | P78334 | 2/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARD | Q03181 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5084376 | 0.82 | MMP1 (0.33) | AKR1B1GPR84PPARDFFAR1FFAR4 | |
| SCHEMBL8395555 | 0.81 | MMP1 (0.47) | ALDH1A1HSD17B10 | |
| SCHEMBL5432078 | 0.80 | KDM4C (0.41) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL7141671 | 0.79 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL11342740 | 0.78 | AKR1B1 (0.46) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL24114955 | 0.77 | OPRM1 (0.35) | TSHRALDH1A1 | |
| SCHEMBL4939550 | 0.76 | KDM5A (0.44) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL5283650 | 0.75 | AKR1B1 (0.52) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3104058 | 0.75 | ALDH1A1 (0.38) | TSHRALDH1A1MEN1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL14889209 | 0.74 | DNM1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748310-B1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO SPA (IT) | 1999-06-02 | — | — | EP | disclosed |
| US-5827881-A | ADMINISTERING FOR TREATMENT OF VIRAL DISEASES OR AS ANTIINFLAMMATORY AGENTS | ITALFARMACO S.P.A. (IT) | 1998-10-27 | — | — | US | disclosed |
| CN-1142222-A | Diesters of carbonic acid endowed with antiviral and anti-inflammatory activity | ITALFARMACO SPA (IT) | 1997-02-05 | — | — | CN | disclosed |
| EP-0748310-A1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO S.p.A. (IT) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023128-A1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO S.P.A. (IT) | 1995-08-31 | — | — | WO | disclosed |