Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481906 | 0.81 | SIGMAR1 (0.46) | SIGMAR1 | |
| SCHEMBL27496330 | 0.76 | LMNA (0.34) | ALDH1A1 | |
| SCHEMBL23510689 | 0.74 | NOS1 (0.41) | SIGMAR1NOS1ALDH1A1 | |
| SCHEMBL9485990 | 0.71 | CCR5 (0.42) | SIGMAR1ALOX15HSP90AA1TLR9ALDH1A1 | |
| SCHEMBL27427343 | 0.69 | SIGMAR1 (0.48) | SIGMAR1ALOX15HSP90AA1TLR9ALDH1A1 | |
| SCHEMBL16167178 | 0.68 | SIGMAR1 (0.41) | SIGMAR1HSP90AA1TLR9ALDH1A1 | |
| SCHEMBL6728165 | 0.65 | SIGMAR1 (0.67) | SIGMAR1 | |
| SCHEMBL3663002 | 0.64 | DGAT1 (0.38) | SIGMAR1ALOX15HSP90AA1TLR9ALDH1A1 | |
| SCHEMBL23517155 | 0.62 | SIGMAR1 (0.53) | SIGMAR1ALDH1A1 | |
| SCHEMBL27496662 | 0.61 | SIGMAR1 (0.46) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1126434-A | Therapeutic substituted guanidines | CAMBRIDGE NEUROSCIENCE INC (US) | 1996-07-10 | — | — | CN | disclosed |